A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.

Much of the variation in inherited risk of colorectal cancer (CRC) is probably due to combinations of common low risk variants. We conducted a genome-wide association study of 550,000 tag SNPs in 930 familial colorectal tumor cases and 960 controls. The most strongly associated SNP (P = 1.72 x 10(-7...

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Detalhes bibliográficos
Principais autores:	Tomlinson, I, Webb, E, Carvajal-Carmona, L, Broderick, P, Kemp, Z, Spain, S, Penegar, S, Chandler, I, Gorman, M, Wood, W, Barclay, E, Lubbe, S, Martin, L, Sellick, G, Jaeger, E, Hubner, R, Wild, R, Rowan, A, Fielding, S, Howarth, K, Silver, A, Atkin, W, Muir, K, Logan, R, Kerr, D
Formato:	Journal article
Idioma:	English
Publicado em:	2007

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.

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