Optimizing parallel induction of HIV type 1-specific antibody and T-cell responses by multicomponent subunit vaccines.

OBJECTIVES:: Protection against HIV type 1 (HIV-1) infection/AIDS will likely require concerted actions of protective CD8 killer T cells and protective antibodies. The challenges in inducing such effectors by active immunization are such that the T-cell and antibody vaccine components require separa...

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Detalhes bibliográficos
Principais autores: Clutton, G, Carpov, A, Parks, C, Dean, H, Montefiori, D, Hanke, T
Formato: Journal article
Idioma:English
Publicado em: Lippincott Williams and Wilkins 2014