Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis

Mutations in Mycobacterium tuberculosis associated with resistance to antibiotics often come with a fitness cost for the bacteria. Resistance to the first-line drug rifampicin leads to lower competitive fitness of M. tuberculosis populations when compared to susceptible populations. This fitness cos...

Full description

Bibliographic Details
Main Authors: Brunner, V, Fowler, P
Format: Journal article
Language:English
Published: Microbiology Society 2024