Compensatory mutations are associated with increased in vitro growth in resistant clinical samples of Mycobacterium tuberculosis
Mutations in Mycobacterium tuberculosis associated with resistance to antibiotics often come with a fitness cost for the bacteria. Resistance to the first-line drug rifampicin leads to lower competitive fitness of M. tuberculosis populations when compared to susceptible populations. This fitness cos...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
Microbiology Society
2024
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