Interferon induction held captive in tumor cells
Unusual nucleic acids activate innate immunity and may be present in transformed cells. Meng et al., 2021 find that cancer-associated mutations in NF2 turn this tumor suppressor into a potent antagonist of DNA- and RNA-induced innate immune signaling.
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Cell Press
2021
|