Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

Isotope labels are frequently used tools to track metabolites through complex biochemical pathways and to discern the mechanisms of enzyme-catalysed reactions. Isotopically-labelled L-serine is often used to monitor the activity of the first enzyme in sphingolipid biosynthesis, serine palmitoyltrans...

書誌詳細
主要な著者:	Harrison, PJ, Gable, K, Somashekarappa, N, Kelly, V, Clarke, DJ, Naismith, JH, Dunn, TM, Campopiano, DJ
フォーマット:	Journal article
言語:	English
出版事項:	American Society for Biochemistry and Molecular Biology 2019

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