Placental stress and pre-eclampsia: a revised view.

In pre-eclampsia, poor placentation causes both oxidative and endoplasmic reticulum stress of the placenta. It is believed placental hypoxia stimulates excessive production of soluble fms-like tyrosine kinase 1 (sFlt-1), which binds and deactivates circulating vascular endothelial growth factor (VEG...

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Bibliographic Details
Main Authors: Redman, C, Sargent, I
Format: Journal article
Language:English
Published: 2009