Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity.

Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with the associated risks of accidental release or in...

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Bibliographic Details
Main Authors: Porta, C, Xu, X, Loureiro, S, Paramasivam, S, Ren, J, Al-Khalil, T, Burman, A, Jackson, T, Belsham, G, Curry, S, Lomonossoff, G, Parida, S, Paton, D, Li, Y, Wilsden, G, Ferris, N, Owens, R, Kotecha, A, Fry, E, Stuart, D, Charleston, B, Jones, I
Format: Journal article
Language:English
Published: 2013