A mouse systems genetics approach reveals common and uncommon genetic modifiers of hepatic lysosomal enzyme activities and glycosphingolipids

Identification of genetic modulators of lysosomal enzyme activities and glycosphingolipids (GSLs) may facilitate the development of therapeutics for diseases in which they participate, in-cluding Lysosomal Storage Disorders (LSDs). To this end, we used a systems genetics approach: we measured 11 hep...

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Bibliographic Details
Main Authors: Durán, A, Priestman, D, Las Heras, M, Rebolledo-Jaramillo, B, Olguín, V, Calderón, JF, Zanlungo, S, Gutiérrez, J, Platt, F, Klein, AD
Format: Journal article
Language:English
Published: MDPI 2023