Modelling of the microglial response to neuronal α-synuclein aggregation
Parkinson’s disease is the second most common neurodegenerative disease, characterised by α-synuclein aggregation and loss of dopaminergic and other types of neurons. Inflammation, the activation of microglial and other immune cells in response to pathology, is a well-documented feature of the neur...
Autore principale: | Katsikoudi, A |
---|---|
Altri autori: | Tofaris, G |
Natura: | Tesi |
Lingua: | English |
Pubblicazione: |
2022
|
Soggetti: |
Documenti analoghi
Documenti analoghi
-
Cholestanol accelerates α-synuclein aggregation and spreading by activating asparagine endopeptidase
di: Ting Yu, et al.
Pubblicazione: (2023-11-01) -
Optogenetic-mediated induction and monitoring of α-synuclein aggregation in cellular models of Parkinson’s disease
di: Maxime Teixeira, et al.
Pubblicazione: (2023-12-01) -
Protocol for generation of PD-modeling-induced neurons and detection of α-synuclein forms
di: Francesco V. Nardi, et al.
Pubblicazione: (2024-12-01) -
Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue
di: Iva Stojkovska, et al.
Pubblicazione: (2021-03-01) -
Mechanistic impacts of bacterial diet on dopaminergic neurodegeneration in a Caenorhabditis elegans α-synuclein model of Parkinson’s disease
di: Anthony L. Gaeta, et al.
Pubblicazione: (2023-06-01)