Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.

Amphiphile selection is a critical step for structural studies of membrane proteins (MPs). We have developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from conventional detergents and previously developed FAs. The unique FAs stabilize MPs and form relatively s...

Full description

Bibliographic Details
Main Authors: Lee, S, Bennett, B, Hong, W, Fu, Y, Baker, K, Marcoux, J, Robinson, C, Ward, AB, Halpert, JR, Stevens, R, Stout, C, Yeager, M, Zhang, Q
Format: Journal article
Language:English
Published: 2013