ASYMMETRIC-SYNTHESIS OF THE TAXOL AND TAXOTERE C-13 SIDE-CHAINS

ASYMMETRIC-SYNTHESIS OF THE TAXOL AND TAXOTERE C-13 SIDE-CHAINS

A practical and efficient asymmetric synthesis of the 3-benzoylamino-2- hydroxy-3-phenylpropionic acid derived side chain of the important anticancer agent taxol is described. The pivotal synthetic transformation relies upon the highly diastereoselective tandem lithium amide conjugate addition-elect...

Podrobná bibliografie
Hlavní autoři:	Bunnage, M, Davies, S, Goodwin, C
Médium:	Journal article
Jazyk:	English
Vydáno:	1994

Podobné jednotky

ASYMMETRIC-SYNTHESIS OF HOMOCHIRAL SYN-3-PHENYLISOSERINE AND ANTI-3-PHENYLISOSERINE DERIVATIVES - A PRACTICAL STRATEGY FOR THE SYNTHESIS OF THE TAXOL C-13 SIDE-CHAIN
Autor: Bunnage, M, a další
Vydáno: (1993)

ASYMMETRIC-SYNTHESIS OF ALLOPHENYLNORSTATINE
Autor: Bunnage, M, a další
Vydáno: (1993)

AN EXPEDITIOUS ASYMMETRIC-SYNTHESIS OF ALLOPHENYLNORSTATINE
Autor: Bunnage, M, a další
Vydáno: (1994)

Synthesis of the Taxol core using asymmetric 1,4-additions
Autor: Wang, JY
Vydáno: (2020)

ASYMMETRIC-SYNTHESIS OF BETA-AMINO-ALPHA-HYDROXY ACIDS VIA DIASTEREOSELECTIVE HYDROXYLATION OF HOMOCHIRAL BETA-AMINO ENOLATES
Autor: Bunnage, M, a další
Vydáno: (1994)

ASYMMETRIC-SYNTHESIS OF (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID - THE UNKNOWN AMINO-ACID COMPONENT OF MICROGININ
Autor: Bunnage, M, a další
Vydáno: (1994)

ASYMMETRIC MICHAEL ADDITIONS OF HOMOCHIRAL MAGNESIUM AMIDES
Autor: Bunnage, M, a další
Vydáno: (1994)

ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID
Autor: Bunnage, M, a další
Vydáno: (1995)

Synthesis of the taxol core via catalytic asymmetric 1,4-addition of an Alkylzirconium Nucleophile
Autor: Wang, JYJ, a další
Vydáno: (2020)

Streamlined synthesis of taxol analogues
Autor: Rodriguez, P
Vydáno: (2017)

Rapid synthesis of the Taxol core
Autor: Thomas, P
Vydáno: (2019)

The role of Taxotere in adjuvant therapy for early breast cancer
Autor: I. V. Kolyadina, a další
Vydáno: (2014-07-01)

An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds
Autor: M. L. Marin, a další
Vydáno: (1998-02-01)

Side Effect Of 5-Hydroxytriptamine Receptor Antagonist In The Prophylactic Treatment Of Emesis Induced By Cisplatin And Taxotere Chemotherapy A Case Report.
Autor: Djunaedi, Mochamad, a další
Vydáno: (2006)

Enhancing taxol delivery with novel taxol conjugated liposomal nanoparticles
Autor: Soh, Hua Xiang.
Vydáno: (2011)

Efficacy of Taxotere, Thalidomide, and Prednisolone in Patients with Hormone-Resistant Metastatic Prostate Cancer
Autor: Hamid Rezvani, a další
Vydáno: (2012-11-01)

Asymmetric synthesis of the cis- and trans-stereoisomers of 4-aminopyrrolidine-3-carboxylic acid and 4-aminotetrahydrofuran-3-carboxylic acid.
Autor: Bunnage, M, a další
Vydáno: (2004)

Asymmetric synthesis of anti-(2S,3S)- and syn-(2R,3S)-diaminobutanoic acid.
Autor: Bunnage, M, a další
Vydáno: (2003)

A brief history of taxol
Autor: Justyna Żwawiak, a další
Vydáno: (2014-03-01)

The Effect of Docetaxel (Taxotere®) on Human Gastric Cancer Cells Exhibiting Low-Dose Radiation Hypersensitivity
Autor: Elizabeth K. Balcer-Kubiczek Ph.D., a další
Vydáno: (2008-01-01)

Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells
Autor: Li Ran, a další
Vydáno: (2005-01-01)

TAXOTERE: UPDATE (REVIEW OF REPORTS AT THE 31st ANNUAL SYMPOSIUM ON BREAST CANCER (San Antonio, USA)
Autor: M. B. Stenina
Vydáno: (2014-09-01)

Blood, Toil, and Taxoteres: Biological Determinants of Treatment-Induced ctDNA Dynamics for Interpreting Tumor Response
Autor: Christopher T. Boniface, a další
Vydáno: (2022-05-01)

Regulation of Microtubule, Apoptosis, and Cell Cycle-Related Genes by Taxotere in Prostate Cancer Cells Analyzed by Microarray
Autor: Yiwei Li, a další
Vydáno: (2004-03-01)

Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
Autor: Riker Adam I, a další
Vydáno: (2010-02-01)

Fungal endophytes of Taxus species and regulatory effect of two strains on taxol synthesis
Autor: Hongshan Zhang, a další
Vydáno: (2024-08-01)

Corrigendum: Blood, toil, and taxoteres: Biological determinants of treatment-induced ctDNA dynamics for interpreting tumor response
Autor: Christopher T. Boniface, a další
Vydáno: (2023-03-01)

Efficiency of combining pomegranate juice with low-doses of cisplatin and taxotere on A549 human lung adenocarcinoma cells
Autor: Nasser Mohamad, a další
Vydáno: (2018-01-01)

A meta Analysis of Aidi Injection plus Taxotere and Cisplatin in the Treatment of Non-small Cell Lung Cancer
Autor: Quan WANG, a další
Vydáno: (2010-11-01)

Conjugation of <i>Aspergillus flavipes</i> Taxol with Porphyrin Increases the Anticancer Activity of Taxol and Ameliorates Its Cytotoxic Effects
Autor: Ashraf S. A. El-Sayed, a další
Vydáno: (2020-01-01)

Asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C
Autor: Davies, S, a další
Vydáno: (2013)

Transcriptome Sequencing Reveals Regulatory Mechanisms of Taxol Synthesis in Taxus wallichiana var. Mairei
Autor: Tao Wang, a další
Vydáno: (2019-01-01)

Taxol acts differently on different tubulin isotypes
Autor: Yean Ming Chew, a další
Vydáno: (2023-09-01)

Taxol crystals can masquerade as stabilized microtubules.
Autor: Margit Foss, a další
Vydáno: (2008-01-01)

The effects of taxol in cervical cancer cells hela /
Autor: Anis Atiqah Sakmani, 1993-, author 609188, a další
Vydáno: (2016)

The effects of taxol in cervical cancer cells hela /
Autor: Anis Atiqah Sakmani, 1993-, author 609188
Vydáno: (2016)

Asymmetric synthesis of (1R,2S,3R)-3-methylcispentacin and (1S,2S,3R)-3-methyltranspentacin by kinetic resolution of tert-butyl (+/-)-3-methylcyclopentene-1-carboxylate.
Autor: Bunnage, M, a další
Vydáno: (2003)

Acute Respiratory Distress Syndrome after Treatment of Metastatic Prostate Cancer with Taxotere: A Case Report and Literature Review
Autor: Ali Raufi, a další
Vydáno: (2015-01-01)

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells
Autor: Reza Taheri-Ledari, a další
Vydáno: (2022-09-01)

Darkness: A Crucial Factor in Fungal Taxol Production
Autor: Sameh S. M. Soliman, a další
Vydáno: (2018-03-01)