ASYMMETRIC-SYNTHESIS OF THE TAXOL AND TAXOTERE C-13 SIDE-CHAINS

ASYMMETRIC-SYNTHESIS OF THE TAXOL AND TAXOTERE C-13 SIDE-CHAINS

A practical and efficient asymmetric synthesis of the 3-benzoylamino-2- hydroxy-3-phenylpropionic acid derived side chain of the important anticancer agent taxol is described. The pivotal synthetic transformation relies upon the highly diastereoselective tandem lithium amide conjugate addition-elect...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Bunnage, M, Davies, S, Goodwin, C
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	1994

Những quyển sách tương tự

ASYMMETRIC-SYNTHESIS OF HOMOCHIRAL SYN-3-PHENYLISOSERINE AND ANTI-3-PHENYLISOSERINE DERIVATIVES - A PRACTICAL STRATEGY FOR THE SYNTHESIS OF THE TAXOL C-13 SIDE-CHAIN
Bằng: Bunnage, M, et al.
Được phát hành: (1993)

ASYMMETRIC-SYNTHESIS OF ALLOPHENYLNORSTATINE
Bằng: Bunnage, M, et al.
Được phát hành: (1993)

AN EXPEDITIOUS ASYMMETRIC-SYNTHESIS OF ALLOPHENYLNORSTATINE
Bằng: Bunnage, M, et al.
Được phát hành: (1994)

Synthesis of the Taxol core using asymmetric 1,4-additions
Bằng: Wang, JY
Được phát hành: (2020)

ASYMMETRIC-SYNTHESIS OF BETA-AMINO-ALPHA-HYDROXY ACIDS VIA DIASTEREOSELECTIVE HYDROXYLATION OF HOMOCHIRAL BETA-AMINO ENOLATES
Bằng: Bunnage, M, et al.
Được phát hành: (1994)

ASYMMETRIC-SYNTHESIS OF (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID - THE UNKNOWN AMINO-ACID COMPONENT OF MICROGININ
Bằng: Bunnage, M, et al.
Được phát hành: (1994)

ASYMMETRIC MICHAEL ADDITIONS OF HOMOCHIRAL MAGNESIUM AMIDES
Bằng: Bunnage, M, et al.
Được phát hành: (1994)

ASYMMETRIC-SYNTHESIS OF THE N-TERMINAL COMPONENT OF MICROGININ - (2S,3R)-3-AMINO-2-HYDROXYDECANOIC ACID, ITS (2R,3R)-EPIMER AND (3R)-3-AMINODECANOIC ACID
Bằng: Bunnage, M, et al.
Được phát hành: (1995)

Synthesis of the taxol core via catalytic asymmetric 1,4-addition of an Alkylzirconium Nucleophile
Bằng: Wang, JYJ, et al.
Được phát hành: (2020)

Streamlined synthesis of taxol analogues
Bằng: Rodriguez, P
Được phát hành: (2017)

Rapid synthesis of the Taxol core
Bằng: Thomas, P
Được phát hành: (2019)

The role of Taxotere in adjuvant therapy for early breast cancer
Bằng: I. V. Kolyadina, et al.
Được phát hành: (2014-07-01)

An Asymmetric Synthetic Approach to the A-ring of the Taxol Family of Anti-Cancer Compounds
Bằng: M. L. Marin, et al.
Được phát hành: (1998-02-01)

Side Effect Of 5-Hydroxytriptamine Receptor Antagonist In The Prophylactic Treatment Of Emesis Induced By Cisplatin And Taxotere Chemotherapy A Case Report.
Bằng: Djunaedi, Mochamad, et al.
Được phát hành: (2006)

Enhancing taxol delivery with novel taxol conjugated liposomal nanoparticles
Bằng: Soh, Hua Xiang.
Được phát hành: (2011)

Efficacy of Taxotere, Thalidomide, and Prednisolone in Patients with Hormone-Resistant Metastatic Prostate Cancer
Bằng: Hamid Rezvani, et al.
Được phát hành: (2012-11-01)

Asymmetric synthesis of the cis- and trans-stereoisomers of 4-aminopyrrolidine-3-carboxylic acid and 4-aminotetrahydrofuran-3-carboxylic acid.
Bằng: Bunnage, M, et al.
Được phát hành: (2004)

Asymmetric synthesis of anti-(2S,3S)- and syn-(2R,3S)-diaminobutanoic acid.
Bằng: Bunnage, M, et al.
Được phát hành: (2003)

A brief history of taxol
Bằng: Justyna Żwawiak, et al.
Được phát hành: (2014-03-01)

The Effect of Docetaxel (Taxotere®) on Human Gastric Cancer Cells Exhibiting Low-Dose Radiation Hypersensitivity
Bằng: Elizabeth K. Balcer-Kubiczek Ph.D., et al.
Được phát hành: (2008-01-01)

Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells
Bằng: Li Ran, et al.
Được phát hành: (2005-01-01)

TAXOTERE: UPDATE (REVIEW OF REPORTS AT THE 31st ANNUAL SYMPOSIUM ON BREAST CANCER (San Antonio, USA)
Bằng: M. B. Stenina
Được phát hành: (2014-09-01)

Blood, Toil, and Taxoteres: Biological Determinants of Treatment-Induced ctDNA Dynamics for Interpreting Tumor Response
Bằng: Christopher T. Boniface, et al.
Được phát hành: (2022-05-01)

Regulation of Microtubule, Apoptosis, and Cell Cycle-Related Genes by Taxotere in Prostate Cancer Cells Analyzed by Microarray
Bằng: Yiwei Li, et al.
Được phát hành: (2004-03-01)

Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol
Bằng: Riker Adam I, et al.
Được phát hành: (2010-02-01)

Fungal endophytes of Taxus species and regulatory effect of two strains on taxol synthesis
Bằng: Hongshan Zhang, et al.
Được phát hành: (2024-08-01)

Corrigendum: Blood, toil, and taxoteres: Biological determinants of treatment-induced ctDNA dynamics for interpreting tumor response
Bằng: Christopher T. Boniface, et al.
Được phát hành: (2023-03-01)

Efficiency of combining pomegranate juice with low-doses of cisplatin and taxotere on A549 human lung adenocarcinoma cells
Bằng: Nasser Mohamad, et al.
Được phát hành: (2018-01-01)

A meta Analysis of Aidi Injection plus Taxotere and Cisplatin in the Treatment of Non-small Cell Lung Cancer
Bằng: Quan WANG, et al.
Được phát hành: (2010-11-01)

Conjugation of <i>Aspergillus flavipes</i> Taxol with Porphyrin Increases the Anticancer Activity of Taxol and Ameliorates Its Cytotoxic Effects
Bằng: Ashraf S. A. El-Sayed, et al.
Được phát hành: (2020-01-01)

Asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C
Bằng: Davies, S, et al.
Được phát hành: (2013)

Transcriptome Sequencing Reveals Regulatory Mechanisms of Taxol Synthesis in Taxus wallichiana var. Mairei
Bằng: Tao Wang, et al.
Được phát hành: (2019-01-01)

Taxol acts differently on different tubulin isotypes
Bằng: Yean Ming Chew, et al.
Được phát hành: (2023-09-01)

Taxol crystals can masquerade as stabilized microtubules.
Bằng: Margit Foss, et al.
Được phát hành: (2008-01-01)

The effects of taxol in cervical cancer cells hela /
Bằng: Anis Atiqah Sakmani, 1993-, author 609188, et al.
Được phát hành: (2016)

The effects of taxol in cervical cancer cells hela /
Bằng: Anis Atiqah Sakmani, 1993-, author 609188
Được phát hành: (2016)

Asymmetric synthesis of (1R,2S,3R)-3-methylcispentacin and (1S,2S,3R)-3-methyltranspentacin by kinetic resolution of tert-butyl (+/-)-3-methylcyclopentene-1-carboxylate.
Bằng: Bunnage, M, et al.
Được phát hành: (2003)

Acute Respiratory Distress Syndrome after Treatment of Metastatic Prostate Cancer with Taxotere: A Case Report and Literature Review
Bằng: Ali Raufi, et al.
Được phát hành: (2015-01-01)

A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)2 and taxotere in ovarian cancer cells
Bằng: Reza Taheri-Ledari, et al.
Được phát hành: (2022-09-01)

Darkness: A Crucial Factor in Fungal Taxol Production
Bằng: Sameh S. M. Soliman, et al.
Được phát hành: (2018-03-01)