DSas-6 and Ana2 coassemble into tubules to promote centriole duplication and engagement.
Centrioles form cilia and centrosomes, organelles whose dysfunction is increasingly linked to human disease. Centriole duplication relies on a few conserved proteins (ZYG-1/Sak/Plk4, SAS-6, SAS-5/Ana2, and SAS-4), and is often initiated by the formation of an inner "cartwheel" structure. H...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2010
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