CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines.

Synthetic nonmethylated oligonucleotides containing CpG dinucleotides (CpG-ODNs) have been shown to exhibit immunostimulatory activity. CpG-ODNs have the capacity to directly activate B cells, macrophages, and dendritic cells, and we show here that this is reflected by cell surface binding of oligon...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Oxenius, A, Martinic, M, Hengartner, H, Klenerman, P
פורמט: Journal article
שפה:English
יצא לאור: 1999