Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.

Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells.

FOXP2 mutation causes a severe inherited speech and language defect, while the related transcription factors FOXP1, FOXP3 and FOXP4 are implicated in cancer. FOXP2 mRNA and protein expression were characterised in normal human tissues, haematological cell lines and multiple myeloma (MM) patients...

Bibliográfalaš dieđut
Váldodahkkit:	Campbell, A, Lyne, L, Brown, P, Launchbury, R, Bignone, P, Chi, J, Roncador, G, Lawrie, C, Gatter, K, Kusec, R, Banham, A
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2010

Geahča maid

Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells: Research paper
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Expression of FOXP2 is up-regulated in lymphoid malignancies
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FOXP3+ regulatory T cells as biomarkers in human malignancies.
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The FOXP1 transcription factor is expressed in the majority of follicular lymphomas but is rarely expressed in classical and lymphocyte predominant Hodgkin's lymphoma.
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Defense of the clone: antibody 259D effectively labels human FOXP3 in a variety of applications.
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Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas.
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Is FOXP3 expressed in cutaneous T-cell lymphomas?
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Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.
Dahkki: Banham, A, et al.
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Monoclonal antibodies raised to the human FOXP3 protein can be used effectively for detecting Foxp3(+) T cells in other mammalian species.
Dahkki: Banham, A, et al.
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The FOXP3 transcription factor as a regulatory T-cell marker
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Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma
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N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells.
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FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures
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Characterization of human FOXP1 isoform 2, using monoclonal antibody 4E3-G11, and intron retention as a tissue-specific mechanism generating a novel FOXP1 isoform.
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Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor alpha and improved survival in primary human breast carcinomas.
Dahkki: Fox, S, et al.
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The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
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Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1alpha expression.
Dahkki: Giatromanolaki, A, et al.
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FOXP3 expression in B and T cell lymphomas.
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Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.
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The forkhead transcription factor FOXP2 is required for regulation of p21WAF1/CIP1 in 143B osteosarcoma cell growth arrest
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FOXP1 abnormalities in lymphoma: translocation breakpoint mapping reveals insights into deregulated transcriptional control.
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FOXP1 abnormalities in lymphoma: Translocation breakpoint mapping reveals insights into deregulated transcriptional control
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The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer.
Dahkki: Giatromanolaki, A, et al.
Almmustuhtton: (2008)

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells
Dahkki: Philip J. Brown, et al.
Almmustuhtton: (2016-07-01)

Therapeutic targeting of FOXP3-positive regulatory T cells using a FOXP3 peptide vaccine WO2008081581.
Dahkki: Banham, A, et al.
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FOXP3, a selective marker for a subset of adult T-cell leukaemia/lymphoma.
Dahkki: Roncador, G, et al.
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Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level.
Dahkki: Roncador, G, et al.
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An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning.
Dahkki: French, C, et al.
Almmustuhtton: (2012)

An aetiological Foxp2 mutation causes aberrant striatal activity and alters plasticity during skill learning
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t(3;14)(p14;q32) results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma.
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Expression of the forkhead box transcription factor FOXP1 is associated with oestrogen receptor alpha, oestrogen receptor beta and improved survival in familial breast cancers.
Dahkki: Rayoo, M, et al.
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In reply [2]
Dahkki: Bates, G, et al.
Almmustuhtton: (2007)

FOXP1: a potential therapeutic target in cancer.
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Almmustuhtton: (2007)

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients
Dahkki: Wong, K, et al.
Almmustuhtton: (2014)

Reciprocal expression of the endocytic protein HIP1R and its repressor FOXP1 predicts outcome in R-CHOP-treated diffuse large B-cell lymphoma patients.
Dahkki: Wong, K, et al.
Almmustuhtton: (2014)

The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest.
Dahkki: Duncan M Gascoyne, et al.
Almmustuhtton: (2015-01-01)

Comparison of Choi and Hans' algorithms by immunohistochemistry and quantitative reverse transcriptase-PCR - letter.
Dahkki: Ballabio, E, et al.
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The significance of FOXP1 in diffuse large B-cell lymphoma
Dahkki: Gascoyne, D, et al.
Almmustuhtton: (2016)

High numbers of tumor-infiltrating FOXP3-positive regulatory T cells are associated with improved overall survival in follicular lymphoma.
Dahkki: Carreras, J, et al.
Almmustuhtton: (2006)

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas
Dahkki: Brown, P, et al.
Almmustuhtton: (2015)