Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia

Decreased autophagy contributes to malignancies; however, it is unclear how autophagy has an impact on tumor growth. Acute myeloid leukemia (AML) is an ideal model to address this as (i) patient samples are easily accessible, (ii) the hematopoietic stem and progenitor cells (HSPC) where transformati...

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Bibliographic Details
Main Authors: Simon, A, Watson, A
Format: Journal article
Published: Nature Publishing Group 2015