Themis2: setting the threshold for B-cell selection.

The strength of signal downstream of the B-cell receptor (BCR) determines the positive and negative selection of B cells. Expression of a functional BCR is required for the selection of immature B cells into the peripheral repertoire in the absence of antigen; but selection is also modulated by avid...

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Váldodahkkit: Deobagkar-Lele, M, Anzilotti, C, Cornall, R
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Nature Publishing Group 2017