Themis2: setting the threshold for B-cell selection.
The strength of signal downstream of the B-cell receptor (BCR) determines the positive and negative selection of B cells. Expression of a functional BCR is required for the selection of immature B cells into the peripheral repertoire in the absence of antigen; but selection is also modulated by avid...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Nature Publishing Group
2017
|