Thermodynamics of HMGB1 interaction with duplex DNA.
The high mobility group protein HMGB1 is a small, highly abundant protein that binds to DNA in a non-sequence-specific manner. HMGB1 consists of 2 DNA binding domains, the HMG boxes A and B, followed by a short basic region and a continuous stretch of 30 glutamate or aspartate residues. Isothermal t...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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