Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium vibrio vulnificus

<p style="text-align:justify;"> Hereditary hemochromatosis, an iron overload disease caused by a deficiency in the iron-regulatory hormone hepcidin, is associated with lethal infections by siderophilic bacteria. To elucidate the mechanisms of this susceptibility, we infected wild-ty...

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Bibliographic Details
Main Authors: Arezes, J, Jung, G, Gabayan, V, Valore, E, Ruchala, P, Gulig, P, Ganz, T, Nemeth, E, Bulut, Y
Format: Journal article
Language:English
Published: Elsevier 2015