Structure of the Lassa virus glycan shield provides a model for immunological resistance

Lassa virus is an Old World arenavirus endemic to West Africa that causes severe hemorrhagic fever. Vaccine development has focused on the envelope glycoprotein complex (GPC) that extends from the virion envelope. The often inadequate antibody immune response elicited by both vaccine and natural inf...

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Bibliographic Details
Main Authors: Watanabe, Y, Raghwani, j, Allen, J, Seabright, G, Li, S, Moser, F, Huiskonen, J, Strecker, T, Bowden, T, Crispin, M
Format: Journal article
Language:English
Published: National Academy of Sciences 2018