Induction of interleukin-1 in articular cartilage by explantation and cutting.

Induction of interleukin-1 in articular cartilage by explantation and cutting.

OBJECTIVE: To investigate the effect of explantation and fine cutting of articular cartilage upon intracellular inflammatory signaling pathways and expression of interleukin-1 (IL-1). METHODS: Cartilage from porcine metacarpophalangeal joints was cultured in serum-free medium. Tissue extracts were...

書誌詳細
主要な著者:	Gruber, J, Vincent, T, Hermansson, M, Bolton, M, Wait, R, Saklatvala, J
フォーマット:	Journal article
言語:	English
出版事項:	2004

類似資料

Basic FGF mediates an immediate response of articular cartilage to mechanical injury.
著者:: Vincent, T, 等
出版事項: (2002)

Basic fibroblast growth factor (FGF) mediator of the immediate injury response in articular cartilage
著者:: Vincent, T, 等
出版事項: (2001)

BASIC FIBROBLAST GROWTH FACTOR (bFGF) MEDIATES THE IMMEDIATE INJURY RESPONSE IN ARTICULAR CARTILAGE
著者:: Vincent, T, 等
出版事項: (2002)

Two-dimensional electrophoresis of proteins secreted from articular cartilage.
著者:: Hermansson, M, 等
出版事項: (2007)

Activation of mitogen activated Protein Kinases (MAPKs) and gene induction upon explantation in articular cartilage from wild type and FGF-2(-/-) mice
著者:: Chong, K, 等
出版事項: (2009)

Proteomic analysis of articular cartilage shows increased type II collagen synthesis in osteoarthritis and expression of inhibin betaA (activin A), a regulatory molecule for chondrocytes.
著者:: Hermansson, M, 等
出版事項: (2004)

Profound translational arrest during cyclical loading of porcine articular cartilage is followed by rebound increased protein synthesis in off loaded explants
著者:: Vincent, T, 等
出版事項: (2009)

Apolipoprotein A-1 is a novel inducer of aggrecan breakdown in cultured articular cartilage
著者:: Didangelos, A, 等
出版事項: (2009)

Basic fibroblast growth factor mediates transduction of mechanical signals when articular cartilage is loaded.
著者:: Vincent, T, 等
出版事項: (2004)

Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage.
著者:: Sawaji, Y, 等
出版事項: (2008)

Basic fibroblast growth factor: An extracellular mechanotransducer in articular cartilage?
著者:: Vincent, T, 等
出版事項: (2006)

Basic fibroblast growth factor: an extracellular mechanotransducer in articular cartilage?
著者:: Vincent, T, 等
出版事項: (2006)

Pericellular matrix of articular cartilage. A novel mechanotransduction mechanism in articular chondrocytes?
著者:: Vincent, T, 等
出版事項: (2006)

Structural and regulatory components of the pericellular matrix of young and mature articular cartilage
著者:: McLean, C, 等
出版事項: (2010)

Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaB.
著者:: Alexander, S, 等
出版事項: (2007)

Anti-catabolic effect of fibroblast growth factor-2 in human articular cartilage
著者:: Sawaji, Y, 等
出版事項: (2009)

Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage.
著者:: Watt, F, 等
出版事項: (2012)

Connective tissue growth factor: matrix localisation, regulation and possible function in articular cartilage
著者:: McLean, C, 等
出版事項: (2010)

Articular cartilage injury rapidly activates TAK1 in chondrocytes by inducing its phosphorylation and K63-polyubiquitination
著者:: Ismail, H, 等
出版事項: (2017)

Wounding articular cartilage rapidly activates multiple signalling events in chondrocytes involving protein phosphorylation and polyubiquitination
著者:: Ismail, H, 等
出版事項: (2014)

Dexamethasone inhibits aggrecanolysis in human articular cartilage but promotes it in porcine tissue
著者:: Sawaji, Y, 等
出版事項: (2009)

The c-jun N-terminal kinase (JNK)-2 controls articular cartilage aggrecan degradation and progression of experimental osteoarthritis
著者:: Ismail, H, 等
出版事項: (2014)

Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee
著者:: Masaichi Sotozawa, 等
出版事項: (2023-01-01)

Culturing Articular Cartilage Explants in the Presence of Autologous Adipose Tissue Modifies Their Inflammatory Response to Lipopolysaccharide
著者:: Wendy Pearson, 等
出版事項: (2020-01-01)

FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer.
著者:: Vincent, T, 等
出版事項: (2007)

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis.
著者:: Gardiner, MD, 等
出版事項: (2014)

ARTICULAR CARTILAGE /
著者:: Athanasiou, K. A. (Kyriacos A.), author, 等
出版事項: (2017)

INTERLEUKIN 1 INDUCES AGGRECAN DEGRADATION BY HUMAN ARTICULAR CHONDROCYTES THROUGH A TAK1/MKK4/JNK2 PATHWAY WITHOUT INVOLVEMENT OF NFKB
著者:: Ismail, H, 等
出版事項: (2013)

Articular cartilage /
著者:: Athanasiou, K. A. (Kyriacos A.)
出版事項: (c201)

Nitric oxide mediates interleukin-1 induced inhibition of glycosaminoglycan synthesis in rat articular cartilage
著者:: T. A. H. Järvinen, 等
出版事項: (1995-01-01)

Is the response of cartilage to injury relevant to osteoarthritis?
著者:: Vincent, T, 等
出版事項: (2008)

JNK2 controls aggrecan degradation in murine articular cartilage and the development of experimental osteoarthritis.
著者:: Ismail, H, 等
出版事項: (2015)

Articular cartilage collagen: an irreplaceable framework?
著者:: D R Eyre, 等
出版事項: (2006-11-01)

Tenascin-C fragments are endogenous inducers of cartilage matrix degradation.
著者:: Sofat, N, 等
出版事項: (2012)

Tenascin-C fragments are endogenous inducers of cartilage matrix degradation
著者:: Sofat, N, 等
出版事項: (2011)

Sharp injury to articular cartilage activates JNK and NF kappa B and induces expression of inflammatory response genes
著者:: Watt, F, 等
出版事項: (2006)

The effects of physiological and injurious hydrostatic pressure on murine ex vivo articular and growth plate cartilage explants: an RNAseq study
著者:: Lucie E. Bourne, 等
出版事項: (2023-12-01)

Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study
著者:: Dovile Sinkeviciute, 等
出版事項: (2020-05-01)

Oxygen, nitric oxide and articular cartilage
著者:: B Fermor, 等
出版事項: (2007-04-01)

Imaging of articular cartilage
著者:: Bhawan K Paunipagar, 等
出版事項: (2014-08-01)