Synthesis of terminal ribose analogues of adenosine 5′-diphosphate ribose as probes for the transient receptor potential cation channel TRPM2

TRPM2 (transient receptor potential cation channel, subfamily M, member 2) is a non-selective cation channel involved in the response to oxidative stress and in inflammation. Its role in autoimmune and neurodegenerative diseases makes it an attractive pharmacological target. Binding of the nucleotid...

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Bibliographic Details
Main Authors: Baszczyňski, O, Watt, JM, Rozewitz, MD, Guse, AH, Fliegert, R, Potter, BVL
Format: Journal article
Language:English
Published: American Chemical Society 2019