Optimization of in vitro erythropoiesis from CD34+ cord blood cells using design of experiments (DOE)

In vitro culture studies of hematopoietic cells (HCs) have traditionally been limited to dose-response, empirical methods which can be uninformative, misleading and suboptimal. Herein, we use design of experiments methodology to quantitatively define and optimize in vitro erythropoiesis from human c...

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Bibliographic Details
Main Authors: Lim, M, Panoskaltsis, N, Ye, H, Mantalaris, A
Format: Journal article
Language:English
Published: 2011