Ca2+i and the pancreatic α cell – intrinsic regulation and dysfunction in type 2 diabetes
<p>In type 2 diabetes (T2D), elevated plasma glucagon concentration (hyperglucagonaemia) exacerbates hyperglycaemia due to inappropriate insulin secretion. Despite this, very little is known about why glucagon secreting α cells become dysfunctional.</p> <p>In α cells, intracellula...
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| Formato: | Thesis |
| Idioma: | English |
| Publicado: |
2019
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