Notch signalling in Xenopus laevis haematopoietic stem cell programming

<p>Multipotent haematopoietic stem cells (HSCs) originate in the dorsal aorta (DA) during vertebrate embryogenesis, and after migrating to a permanent niche, give rise to a continuous supply of mature blood cells of all lineages throughout adult life. Previous cell tracing experiments have sho...

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Bibliographic Details
Main Author: Stephenson, RA
Other Authors: Patient, R
Format: Thesis
Language:English
Published: 2013
Subjects: