LAG-3: a very singular immune checkpoint
The mechanism of action of the lymphocyte checkpoint protein LAG-3 was always rather mysterious. It now seems to operate at least in part by recognizing and suppressing responses to stable complexes of peptide and major histocompatibility complex class II.
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2018
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| _version_ | 1826270925742407680 |
|---|---|
| author | Lui, Y Davis, S |
| author_facet | Lui, Y Davis, S |
| author_sort | Lui, Y |
| collection | OXFORD |
| description | The mechanism of action of the lymphocyte checkpoint protein LAG-3 was always rather mysterious. It now seems to operate at least in part by recognizing and suppressing responses to stable complexes of peptide and major histocompatibility complex class II. |
| first_indexed | 2024-03-06T21:48:32Z |
| format | Journal article |
| id | oxford-uuid:4a7168f5-1bfc-44f1-b3ee-7d46d1bd3e2b |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T21:48:32Z |
| publishDate | 2018 |
| publisher | Springer Nature |
| record_format | dspace |
| spelling | oxford-uuid:4a7168f5-1bfc-44f1-b3ee-7d46d1bd3e2b2022-03-26T15:37:31ZLAG-3: a very singular immune checkpointJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:4a7168f5-1bfc-44f1-b3ee-7d46d1bd3e2bEnglishSymplectic Elements at OxfordSpringer Nature2018Lui, YDavis, SThe mechanism of action of the lymphocyte checkpoint protein LAG-3 was always rather mysterious. It now seems to operate at least in part by recognizing and suppressing responses to stable complexes of peptide and major histocompatibility complex class II. |
| spellingShingle | Lui, Y Davis, S LAG-3: a very singular immune checkpoint |
| title | LAG-3: a very singular immune checkpoint |
| title_full | LAG-3: a very singular immune checkpoint |
| title_fullStr | LAG-3: a very singular immune checkpoint |
| title_full_unstemmed | LAG-3: a very singular immune checkpoint |
| title_short | LAG-3: a very singular immune checkpoint |
| title_sort | lag 3 a very singular immune checkpoint |
| work_keys_str_mv | AT luiy lag3averysingularimmunecheckpoint AT daviss lag3averysingularimmunecheckpoint |