Anti-thrombin is expressed in the benign prostatic epithelium and in prostate cancer and is capable of forming complexes with prostate-specific antigen and human glandular kallikrein 2.

Anti-thrombin, a member of the serpin family and an inhibitor of thrombin and blood coagulation factor Xa, was recently shown to inhibit angiogenesis and tumor growth. In the present study, we examined the expression of anti-thrombin in benign and malignant prostate gland. Using immunohistochemistry...

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Bibliographic Details
Main Authors: Cao, Y, Lundwall, A, Gadaleanu, V, Lilja, H, Bjartell, A
Format: Journal article
Language:English
Published: 2002