A rapid and sensitive assay for quantification of siRNA efficiency and specificity.

RNA Interference has rapidly emerged as an efficient procedure for knocking down gene expression in model systems. However, cross-reactivity, whereby multiple genes may be simultaneously targeted by a single short interfering RNA (siRNA), can potentially jeopardize correct interpretation of gene fun...

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Autori principali: Smart, N, Scambler, P, Riley, P
Natura: Journal article
Lingua:English
Pubblicazione: Springer-Verlag 2005