The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes.

Accurate pre-mRNA splicing by the spliceosome is a fundamental cellular mechanism required to remove introns that are present in most protein-coding transcripts. The recent discovery of a variety of somatic spliceosomal mutations in the myelodysplastic syndromes (MDS), a heterogeneous group of myelo...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Boultwood, J, Dolatshad, H, Varanasi, S, Yip, B, Pellagatti, A
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2014