Intravascular haemolysis in severe Plasmodium knowlesi malaria: association with endothelial activation, microvascular dysfunction, and acute kidney injury

Plasmodium knowlesi occurs throughout Southeast Asia, and is the most common cause of human malaria in Malaysia. Severe disease in humans is characterised by high parasite biomass, reduced red blood cell deformability, endothelial activation and microvascular dysfunction. However, the roles of intra...

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Bibliographic Details
Main Authors: Barber, B, Grigg, M, Piera, K, William, T, Cooper, D, Plewes, K, Dondorp, A, Yeo, T, Anstey, N
Format: Journal article
Language:English
Published: Springer Nature 2018