Heat shock protein-based therapy for sphingolipidoses

Lysosomal diseases often manifest with severe systemic and central nervous system (CNS) symptoms. The existing treatment options are limited and have no or only modest efficacy against neurological manifestations of disease. We recently demonstrated that recombinant HSP70 improves the binding of sev...

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Bibliographic Details
Main Authors: Kirkegaard, T, Gray, J, Priestman, D, Wallom, K, Petersen, N, Ingemann, L, Bornæs, C, Drndarski, S, Klein, A, Jørgensen, S, Atkins, J, Olsen, O, Smith, D, Hinsby, A, Arenz, C, Begley, D, Jäättelä, M, Platt, F
Format: Conference item
Published: Elsevier 2017