Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters
A major challenge in drug development is the optimization of intestinal absorption and cellular uptake. A successful strategy has been to develop prodrug molecules, which hijack solute carrier (SLC) transporters for active transport into the body. The proton-coupled oligopeptide transporters, PepT1...
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| Format: | Journal article |
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National Academy of Sciences
2019
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