Regulation of CD40 function by its isoforms generated through alternative splicing.

CD40 is a member of the tumor necrosis factor receptor superfamily. The interaction between CD40 and CD40 ligand (CD154) activates NF-kappa B, Jun N-terminal kinase, and Janus kinase/signal transducers and activators of transcription pathways and promotes B cell growth, differentiation, and survival...

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Bibliographic Details
Main Authors: Tone, M, Tone, Y, Fairchild, P, Wykes, M, Waldmann, H
Format: Journal article
Language:English
Published: 2001