The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling
Background: T-cell membrane scaffold proteins are pivotal in T cell function, acting as versatile signaling hubs. While CD6 forms a large intracellular signalosome, it is distinguished from typical scaffolds like LAT or PAG by possessing a substantial ectodomain that binds CD166, a well-characterize...
| Hauptverfasser: | , , , , , |
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| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
BioMed Central
2024
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