A model invalidation-based approach for elucidating biological signalling pathways, applied to the chemotaxis pathway in R. sphaeroides

<p style="text-align:justify;"> <b>Background:</b> Developing methods for understanding the connectivity of signalling pathways is a major challenge in biological research. For this purpose, mathematical models are routinely developed based on experimental observations,...

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Bibliographic Details
Main Authors: Roberts, MAJ, August, E, Hamadeh, A, Maini, P, McSharry, P, Armitage, J, Papachristodoulou, A
Format: Journal article
Language:English
Published: BioMed Central 2009