Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine.

The RTS,S/SBAS2 vaccine confers sterile protection against Plasmodium falciparum sporozoite challenge. The mechanisms underlying this are of great interest, yet little is known about the immune effector mechanisms induced by this vaccine. The immune responses induced by RTS,S/SBAS2 were characterize...

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Bibliographic Details
Main Authors: Lalvani, A, Moris, P, Voss, G, Pathan, A, Kester, K, Brookes, R, Lee, E, Koutsoukos, M, Plebanski, M, Delchambre, M, Flanagan, K, Carton, C, Slaoui, M, Van Hoecke, C, Ballou, W, Hill, A, Cohen, J
Format: Journal article
Language:English
Published: 1999