Novel and selective small molecule inhibitors and activators for the prolyl hydroxylase domain enzyme

Novel and selective small molecule inhibitors and activators for the prolyl hydroxylase domain enzyme

<p>Hypoxia Inducible Factors (HIF) functions are master regulators of oxygen homeostasis and have a key role in the physiological responses to hypoxia including angiogenesis and erythropoiesis. Under hypoxia, levels of HIF-α subunits increase, they hetereodimerise with HIF-1β sub unit and pr...

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Chi tiết về thư mục
Tác giả chính:	Holt-Martyn, J
Tác giả khác:	Schofield, C
Định dạng:	Luận văn
Được phát hành:	2018

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