The ligand-sensitive gate of a potassium channel lies close to the selectivity filter.

Potassium channels selectively conduct K(+) ions across cell membranes and have key roles in cell excitability. Their opening and closing can be spontaneous or controlled by membrane voltage or ligand binding. We used Ba(2+) as a probe to determine the location of the ligand-sensitive gate in an inw...

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Bibliographic Details
Main Authors: Proks, P, Antcliff, J, Ashcroft, F
Format: Journal article
Language:English
Published: 2003