Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot.

<p><strong>Background</strong>: Epidemiological studies indicate a substantial excess familial recurrence of non-syndromic Tetralogy of Fallot (TOF), implicating genetic factors that remain largely unknown. The Rho induced kinase 1 gene (ROCK1) is a key component of the planar cell...

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Main Authors:	Palomino Doza, J, Topf, A, Bentham, J, Bhattacharya, S, Cosgrove, C, Brook, J, Granados-Riveron, J, Bu'Lock, F, O'Sullivan, J, Stuart, A, Parsons, J, Relton, C, Goodship, J, Henderson, D, Keavney, B
Format:	Journal article
Language:	English
Published:	BioMed Central 2013

Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallot.

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