Leptin and soluble leptin receptor in risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition cohort.

Leptin, a peptide hormone produced primarily by the adipocytes, is hypothesized to play a role in the pathogenesis of colorectal cancer (CRC). Soluble leptin receptor (sOB-R) may regulate leptin's physiologic functions; however its relation to CRC risk is unknown. This study explored the associ...

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Bibliographic Details
Main Authors: Aleksandrova, K, Boeing, H, Jenab, M, Bueno-de-Mesquita, H, Jansen, E, van Duijnhoven, F, Rinaldi, S, Fedirko, V, Romieu, I, Riboli, E, Gunter, M, Westphal, S, Overvad, K, Tjønneland, A, Halkjær, J, Racine, A, Boutron-Ruault, M, Clavel-Chapelon, F, Kaaks, R, Lukanova, A, Trichopoulou, A, Lagiou, P, Trichopoulos, D, Mattiello, A, Pala, V
Format: Journal article
Language:English
Published: 2012