Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.

Multiple sclerosis (MS) susceptibility is characterized by maternal parent-of-origin effects and increased female penetrance. In 7796 individuals from 1797 MS families (affected individuals n = 2954), we further implicate epigenetic modifications within major histocompatibility complex (MHC) class I...

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Váldodahkkit: Chao, M, Herrera, B, Ramagopalan, S, Deluca, G, Handunetthi, L, Orton, S, Lincoln, MR, Sadovnick, A, Ebers, G
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2010