Cytoskeletal protein degradation in brain death donor kidneys associates with adverse posttransplant outcomes

In brain death, cerebral injury contributes to systemic biological dysregulation, causing significant cellular stress in donor kidneys adversely impacting the quality of grafts. Here, we hypothesized that donation after brain death (DBD) kidneys undergo proteolytic processes that may deem grafts sus...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Vaughan, RH, Kresse, J-C, Farmer, LK, Thézénas, ML, Kessler, BM, Lindeman, JHN, Sharples, EJ, Welsh, GI, Nørregaard, R, Ploeg, RJ, Kaisar, ME
Format: Journal article
Sprache:English
Veröffentlicht: Wiley 2022