Regulation of alternative splicing of CD45 by antagonistic effects of SR protein splicing factors.

CD45 is a transmembrane glycoprotein possessing tyrosine phosphatase activity, which is involved in cell signaling. CD45 is expressed on the surface of most leukocytes and can be alternatively spliced by the inclusion or skipping of three variable exons (4, 5, and 6 or A, B, and C) to produce up to...

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Bibliographic Details
Main Authors: ten Dam, G, Zilch, C, Wallace, D, Wieringa, B, Beverley, P, Poels, L, Screaton, G
Format: Journal article
Language:English
Published: 2000