CryoSIM: Super resolution 3D structured illumination cryogenic fluorescence microscopy for correlated ultra-structural imaging

Rapid cryopreservation of biological specimens is the gold standard for visualizing cellular structures in their true structural context. However, current commercial cryo-fluorescence microscopes are limited to low resolutions. To fill this gap, we have developed cryoSIM, a microscope for 3D super-r...

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Bibliographic Details
Main Authors: Phillips, M, Susano Pinto, D, Harkiolaki, M, Parton, R, Palanca, A, Garcia-Moreno, M, Kounatidis, I, Sedat, J, Stuart, D, Castello, A, Booth, M, Davis, I, Dobbie, I
Format: Journal article
Language:English
Published: Optical Society of America 2020