Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo.

Vanadate prevents glucocorticoid-induced apoptosis of osteoblasts in vitro and osteocytes in vivo.

Skeletal mass is maintained by a balance between formation and resorption, cell proliferation and apoptosis. In vitro, glucocorticoids (GCs) decrease extracellular signal-regulated kinases (ERK) activation by mitogens, thus inhibiting osteoblast proliferation. Both ERK activity and proliferation are...

Полное описание

Библиографические подробности
Главные авторы:	Conradie, M, De Wet, H, Kotze, D, Burrin, J, Hough, F, Hulley, P
Формат:	Journal article
Язык:	English
Опубликовано:	2007

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