The cysteinome of protein kinases as a target in drug development

Drugs that function through covalent bond formation represent a considerable fraction of our repository of effective medicines but safety concerns and the complexity of developing covalent inhibitors has rendered covalent targeting a less attractive strategy for rational drug design. The recent appr...

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Bibliographic Details
Main Authors: Chaikuad, A, Koch, P, Laufer, SA, Knapp, S
Format: Journal article
Language:English
Published: Wiley 2018