Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.

CD8⁺ T cells mediate immunity against Plasmodium liver stages. However, the paucity of parasite-specific epitopes of CD8⁺ T cells has limited our current understanding of the mechanisms influencing the generation, maintenance and efficiency of these responses. To identify antigenic epitopes in a str...

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Bibliographic Details
Main Authors: Hafalla, J, Bauza, K, Friesen, J, Gonzalez-Aseguinolaza, G, Hill, A, Matuschewski, K
Format: Journal article
Language:English
Published: Public Library of Science 2013