Structural basis of metallo-β-lactamase inhibition by captopril stereoisomers
β-Lactams are the most successful antibacterials, but their effectiveness is threatened by resistance, most importantly by production of serine- and metallo-β-lactamases (MBLs). MBLs are of increasing concern because they catalyse the hydrolysis of almost all β-lactam antibiotics, including recent g...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Society for Microbiology
2015
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