Structural basis of metallo-β-lactamase inhibition by captopril stereoisomers

β-Lactams are the most successful antibacterials, but their effectiveness is threatened by resistance, most importantly by production of serine- and metallo-β-lactamases (MBLs). MBLs are of increasing concern because they catalyse the hydrolysis of almost all β-lactam antibiotics, including recent g...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Brem, J, van Berkel, S, Zollman, D, Lee, S, Gileadi, O, McHugh, P, Walsh, T, McDonough, M, Schofield, C
বিন্যাস: Journal article
প্রকাশিত: American Society for Microbiology 2015